Chronic Subdural Hematoma in A 2 Years-Old Child A Dark Side in Jacobsen Syndrome

Valentina Baro

Luca Denaro

Andrea Landi

Alberto D’Amico

Nicola Bresolin

Giulia M. Furlanis

Recieved on: 2023-11-11, Accepted on: 2023-12-22, Published on: 2023-12-28

Abstract

Jacobsen Syndrome is a rare genetic disease caused by partial deletion of chromosome 11 and is characterized by mental and motor delay, organs malformation and platelet dysfunction. Even if the intracranial hemorrhage is a real risk in Jacobsen Syndrome, this complication remains an event poorly described and the chronic subdural hematoma (cSDH) is an unknown entity in literature.

We reported a case of a 2-year-old female affected by Jacobsen Syndrome with sudden onset of neurological impairment secondary to a chronic subdural hematoma, resolved with a mini-craniotomy. Furthermore, we have conducted a review of the literature about intracranial hemorrhages in Jacobsen Syndrome. According to our experience, chronic subdural hematoma is a sneaky event, and we suggest taking it in account to improve management of child affected by Jacobsen Syndrome.

Keywords

Jacobsen Syndrome; Pediatric; Chronic subdural Hematoma; Thrombocytopenia; Intracranial bleeding